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Hence, it can be conceivable that the JIP1/3???ASK1???MKK4 signaling module may well serve as a conduit to activate JNK when endosomal trafficking is disrupted and glucose ranges slide in the early levels of methuosis. Our locating that MKK4 was robustly activated because of the methuosis-inducing IPPs, MOMIPP and 2q, and fewer so because of the no

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